What is Letrozole Used For?

Letrozole (Femara) is an oral medication used to stimulate ovulation, treat polycystic ovary syndrome (PCOS) symptoms or for those diagnosed with unexplained infertility. Letrozole’s use will depend on your fertility diagnosis or previous treatment history. It is typically prescribed for a treatment course of 5 days.

How Does Letrozole (Femara) Work?

Letrozole works by inhibiting aromatase and blocking the amount of androgens your body makes which then causes estrogen to decrease. Now your pituitary gland responds by producing follicle-stimulating hormone (FSH) and triggers the ovary to produce an egg.

In women who are ovulating, Letrozole can stimulate the development of multiple follicles and eggs to be released, often known as controlled ovarian hyperstimulation. This improves your chance of pregnancy as compared to a natural menstrual cycle where only one egg is released.

What is Letrozole Used For In Infertility?

Which Drug is Better-Letrozole or Clomid?

When Letrozole is used in combination with intrauterine insemination (IUI), your chances of pregnancy may significantly improve. It also can be an effective medication alternative when clomid has not resulted in a pregnancy success or positive outcome.

In a 2014 NIH funded study, researchers found that women treated with Letrozole as compared to clomophene were more likely to ovulate and had higher chances of a live birth.

Does Letrozole Help You Get Pregnant?

Your chances for pregnancy when using Letrozole may increase according to a 2014 news bulletin based on a large study prepared by the National Institutes of Health. In the research it was shown to be an effective treatment for women with PCOS.


Related Topics

Clomid for Women and Men

Fertility Evaluation

Intrauterine Insemination

In Vitro Fertilization


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